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Cocaine binds tightly with the dopamine transporter forming a complex that blocks the transporter's purpose. The dopamine transporter can now not execute its reuptake purpose, and thus dopamine accumulates inside the synaptic cleft. The amplified concentration of dopamine from the synapse activates article-synaptic dopamine receptors, that makes the drug worthwhile https://aesopw741kry7.wikikali.com/user

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