The recognized impression of those PTMs on ATXN2’s functionality and SCA2 pathogenesis continues to be minimal. In other polyQ disorders, multiple studies instructed that proteolytic cleavage of polyQ proteins could Participate in a very important role in pathogenesis [36, 45]. Aligned with this idea, the existence of an enriched 42 kDa https://joshz221xlw9.aboutyoublog.com/profile